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Paracrine signaling by Platelet Derived Growth Factor-CC promotes tumor growth by recruitment of cancer-associated fibroblasts

Cancer results from the concerted performance of malignant cells and stromal cells. Cell types populating the microenvironment are enlisted by the tumor to secrete a host of growth-promoting cues, thus upholding tumor initiation and progression. Platelet-Derived Growth Factors (PDGFs) support the fo...

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Detalhes bibliográficos
Main Authors: Anderberg, Charlotte, Li, Hong, Fredriksson, Linda, Andrae, Johanna, Betsholtz, Christer, Li, Xuri, Eriksson, Ulf, Pietras, Kristian
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2613547/
https://ncbi.nlm.nih.gov/pubmed/19118022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-2724
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