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Identification of Novel Alternative Splice Isoforms of Circulating Proteins in a Mouse Model of Human Pancreatic Cancer

To assess the potential of tumor-associated alternatively spliced gene products as a source of biomarkers in biological fluids, we have analyzed a large dataset of mass spectra derived from the plasma proteome of a mouse model of human pancreatic ductal adenocarcinoma. MS/MS spectra were interrogate...

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Detalhes bibliográficos
Main Authors: Menon, Rajasree, Zhang, Qing, Zhang, Yan, Fermin, Damian, Bardeesy, Nabeel, DePinho, Ronald A., Lu, Chunxia, Hanash, Samir M., Omenn, Gilbert S., States, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2613545/
https://ncbi.nlm.nih.gov/pubmed/19118015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-2145
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