Epithelial cell α3β1 integrin links β-catenin and Smad signaling to promote myofibroblast formation and pulmonary fibrosis

Pulmonary fibrosis, in particular idiopathic pulmonary fibrosis (IPF), results from aberrant wound healing and scarification. One population of fibroblasts involved in the fibrotic process is thought to originate from lung epithelial cells via epithelial-mesenchymal transition (EMT). Indeed, alveola...

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Detalhes bibliográficos
Main Authors: Kim, Kevin K., Wei, Ying, Szekeres, Charles, Kugler, Matthias C., Wolters, Paul J., Hill, Marla L., Frank, James A., Brumwell, Alexis N., Wheeler, Sarah E., Kreidberg, Jordan A., Chapman, Harold A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2613463/
https://ncbi.nlm.nih.gov/pubmed/19104148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI36940
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