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Role for α3 integrin in EMT and pulmonary fibrosis

Idiopathic pulmonary fibrosis (IPF) is characterized by progressive (myo)fibroblast accumulation and collagen deposition. One possible source of (myo)fibroblasts is epithelial cells that undergo epithelial-mesenchymal transition (EMT), a process frequently mediated by TGF-β. In this issue of the JCI...

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Détails bibliographiques
Auteur principal: Borok, Zea
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2613449/
https://ncbi.nlm.nih.gov/pubmed/19104143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI38084
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