Analysis of EGFR, HER2, and TOP2A gene status and chromosomal polysomy in gastric adenocarcinoma from Chinese patients

BACKGROUND: The EGFR and HER2 genes are located on chromosomes 7 and 17, respectively. They are therapeutic targets in some tumors. The TOP2A gene, which is located near HER2 on chromosome 17, is the target of many chemotherapeutic agents, and co-amplification of HER2 and TOP2A has been described in...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Liang, Zhiyong, Zeng, Xuan, Gao, Jie, Wu, Shafei, Wang, Peng, Shi, Xiaohua, Zhang, Jing, Liu, Tonghua
التنسيق: Artigo
اللغة:Inglês
منشور في: BioMed Central 2008
الموضوعات:
Research Article
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC2613415/
https://ncbi.nlm.nih.gov/pubmed/19061514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-8-363
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