Clinical Correlates, Heritability and Genetic Linkage of Circulating CD40 Ligand in the Framingham Offspring Study

BACKGROUND: The CD40 receptor and its ligand (CD40L) are known to modulate both inflammation and thrombosis, two processes important for the development and clinical expression of atherosclerosis. Circulating soluble CD40L (sCD40L) concentration predicts cardiovascular risk in selected patient sampl...

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Detalhes bibliográficos
Main Authors: Keaney, John F., Lipinska, Izabella, Larson, Martin G., Dupuis, Josée, Freedman, Jane E., Hamburg, Naomi M., Massaro, Joseph M., Rong, Jian, Sutherland, Patrice, Vita, Joseph A., Vasan, Ramachandran S., Benjamin, Emelia J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2613323/
https://ncbi.nlm.nih.gov/pubmed/19061720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ahj.2008.06.041
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