Transcriptional and apoptotic responses of THP-1 cells to challenge with toxigenic, and non-toxigenic Bacillus anthracis

BACKGROUND: Bacillus anthracis secretes several virulence factors targeting different host organs and cell types during inhalational anthrax infection. The bacterial expression of a key virulence factor, lethal toxin (LeTx) is closely tied to another factor, edema toxin (EdTx). Both are transcribed...

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Detalhes bibliográficos
Main Authors: Bradburne, Christopher, Chung, Myung-Chul, Zong, Qin, Schlauch, Karen, Liu, Derong, Popova, Taissia, Popova, Anna, Bailey, Charles, Soppet, Dan, Popov, Serguei
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2613145/
https://ncbi.nlm.nih.gov/pubmed/19014542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2172-9-67
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