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Molecular Clustering of STIM1 with Orai1/CRACM1 at the Plasma Membrane Depends Dynamically on Depletion of Ca(2+) Stores and on Electrostatic Interactions

Activation of store operated Ca(2+) entry involves stromal interaction molecule 1 (STIM1), localized to the endoplasmic reticulum (ER), and calcium channel subunit (Orai1/CRACM1), localized to the plasma membrane. Confocal microscopy shows that thapsigargin-mediated depletion of ER Ca(2+) stores in...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Calloway, Nathaniel, Vig, Monika, Kinet, Jean-Pierre, Holowka, David, Baird, Barbara
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The American Society for Cell Biology 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2613096/
https://ncbi.nlm.nih.gov/pubmed/18987344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-11-1132
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