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Expanding the Mind: Insulin-Like Growth Factor I and Brain Development

Signaling through the type 1 IGF receptor (IGF1R) after interaction with IGF-I is crucial to the normal brain development. Manipulations of the mouse genome leading to changes in the expression of IGF-I or IGF1R significantly alters brain growth, such that IGF-I overexpression leads to brain overgro...

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Detalhes bibliográficos
Main Authors: Joseph D'Ercole, A., Ye, Ping
Formato: Artigo
Idioma:Inglês
Publicado em: The Endocrine Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2613055/
https://ncbi.nlm.nih.gov/pubmed/18687773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2008-0920
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