Malaria Parasite Invasion of the Mosquito Salivary Gland Requires Interaction between the Plasmodium TRAP and the Anopheles Saglin Proteins

SM1 is a twelve-amino-acid peptide that binds tightly to the Anopheles salivary gland and inhibits its invasion by Plasmodium sporozoites. By use of UV-crosslinking experiments between the peptide and its salivary gland target protein, we have identified the Anopheles salivary protein, saglin, as th...

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Detalhes bibliográficos
Main Authors: Ghosh, Anil K., Devenport, Martin, Jethwaney, Deepa, Kalume, Dario E., Pandey, Akhilesh, Anderson, Vernon E., Sultan, Ali A., Kumar, Nirbhay, Jacobs-Lorena, Marcelo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2613030/
https://ncbi.nlm.nih.gov/pubmed/19148273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000265
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