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Loss of both Holliday Junction processing pathways is synthetically lethal in the presence of gonococcal pilin antigenic variation
The obligate human pathogen Neisseria gonorrhoeae (Gc) has co-opted conserved recombination pathways to achieve immune evasion by way of antigenic variation. We show that both the RuvABC and RecG Holliday Junction (HJ) processing pathways are required for recombinational repair, each can act during...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2006
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2612780/ https://ncbi.nlm.nih.gov/pubmed/16824104 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2006.05213.x |
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