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Molecular basis of TRAP–5′SL RNA interaction in the Bacillus subtilis trp operon transcription attenuation mechanism

Expression of the Bacillus subtilis trpEDCFBA operon is regulated by the interaction of tryptophan-activated TRAP with 11 (G/U)AG trinucleotide repeats that lie in the leader region of the nascent trp transcript. Bound TRAP prevents folding of an antiterminator structure and favors formation of an o...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: McGraw, Adam P., Mokdad, Ali, Major, François, Bevilacqua, Philip C., Babitzke, Paul
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2612762/
https://ncbi.nlm.nih.gov/pubmed/19033375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1314409
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