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Probing of Actinobacillus pleuropneumoniae ApxIIIA toxin-dependent cytotoxicity towards mammalian peripheral blood mononucleated cells

BACKGROUND: Actinobacillus pleuropneumoniae, the causative bacterial agent of porcine pleuropneumonia, produces Apx toxins which belong to RTX toxin family and are recognized as the major virulence factors. So far, their target receptor(s) has not been identified and the disease cytopathogenesis rem...

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Bibliografiske detaljer
Main Authors: Vanden Bergh, Philippe GAC, Zecchinon, Laurent LM, Fett, Thomas, Desmecht, Daniel
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2612674/
https://ncbi.nlm.nih.gov/pubmed/19046441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-1-121
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