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Treatment of Venezuelan Equine Encephalitis Virus Infection with (-)-Carbodine

Venezuelan equine encephalitis virus (VEEV) may cause encephalitis in humans, for which no FDA-approved antiviral treatment is available. Carbocyclic cytosine (carbodine) has broad-spectrum activity but toxicity has limited its utility. It was anticipated that one of the enantiomers of carbodine wou...

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Detalhes bibliográficos
Main Authors: Julander, Justin G., Bowen, Richard A., Rao, Jagadeeshwar R., Day, Craig, Shafer, Kristiina, Smee, Donald F., Morrey, John D., Chu, Chung K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2612642/
https://ncbi.nlm.nih.gov/pubmed/18675850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2008.07.002
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