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TRAF2 Phosphorylation Modulates Tumor Necrosis Factor Alpha-Induced Gene Expression and Cell Resistance to Apoptosis
TRAF2 is an adaptor protein that regulates the activation of the c-Jun N-terminal kinase (JNK) and IκB kinase (IKK) signaling cascades in response to tumor necrosis factor alpha (TNF-α) stimulation. Although the downstream events in TNF-α signaling are better understood, the membrane-proximal events...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Microbiology (ASM)
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2612514/ https://ncbi.nlm.nih.gov/pubmed/18981220 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00699-08 |
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