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TRAF2 Phosphorylation Modulates Tumor Necrosis Factor Alpha-Induced Gene Expression and Cell Resistance to Apoptosis

TRAF2 is an adaptor protein that regulates the activation of the c-Jun N-terminal kinase (JNK) and IκB kinase (IKK) signaling cascades in response to tumor necrosis factor alpha (TNF-α) stimulation. Although the downstream events in TNF-α signaling are better understood, the membrane-proximal events...

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Autores principales: Blackwell, Ken, Zhang, Laiqun, Thomas, Gregory S., Sun, Shujie, Nakano, Hiroyasu, Habelhah, Hasem
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2612514/
https://ncbi.nlm.nih.gov/pubmed/18981220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00699-08
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