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Trends in Prokaryotic Evolution Revealed by Comparison of Closely Related Bacterial and Archaeal Genomes

In order to explore microevolutionary trends in bacteria and archaea, we constructed a data set of 41 alignable tight genome clusters (ATGCs). We show that the ratio of the medians of nonsynonymous to synonymous substitution rates (dN/dS) that is used as a measure of the purifying selection pressure...

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Bibliografiske detaljer
Main Authors: Novichkov, Pavel S., Wolf, Yuri I., Dubchak, Inna, Koonin, Eugene V.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2612427/
https://ncbi.nlm.nih.gov/pubmed/18978059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01237-08
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