Double-Stranded RNA Analog Poly(I:C) Inhibits Human Immunodeficiency Virus Amplification in Dendritic Cells via Type I Interferon-Mediated Activation of APOBEC3G

Human immunodeficiency virus (HIV) is taken up by and replicates in immature dendritic cells (imDCs), which can then transfer virus to T cells, amplifying the infection. Strategies known to boost DC function were tested for their ability to overcome this exploitation when added after HIV exposure. P...

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Главные авторы: Trapp, Susanna, Derby, Nina R., Singer, Rachel, Shaw, Andrew, Williams, Vennansha G., Turville, Stuart G., Bess, Julian W., Lifson, Jeffrey D., Robbiani, Melissa
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology (ASM) 2009
Предметы:
Virus-Cell Interactions
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2612396/
https://ncbi.nlm.nih.gov/pubmed/19004943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00023-08
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