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Conformational Changes in the Solution Structure of the Dengue Virus 5′ End in the Presence and Absence of the 3′ Untranslated Region

Dengue virus (DENV) is an ∼10.7-kb positive-sense RNA virus that circularizes via RNA-RNA interactions between sequences in the 5′ and 3′ terminal regions. Complementarity between the cyclization sequence (CS) and the upstream AUG region (UAR) has been shown to be necessary for viral replication. He...

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Detalhes bibliográficos
Main Authors: Polacek, Charlotta, Foley, Jonathan E., Harris, Eva
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2612390/
https://ncbi.nlm.nih.gov/pubmed/19004957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01362-08
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