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Randomization and In Vivo Selection Reveal a GGRG Motif Essential for Packaging Human Immunodeficiency Virus Type 2 RNA

The packaging signal (ψ) of human immunodeficiency virus type 2 (HIV-2) is present in the 5′ noncoding region of RNA and contains a 10-nucleotide palindrome (pal; 5′-392-GGAGUGCUCC) located upstream of the dimerization signal stem-loop 1 (SL1). pal has been shown to be functionally important in vitr...

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Detalhes bibliográficos
Main Authors: Baig, Tayyba T., Lanchy, Jean-Marc, Lodmell, J. Stephen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2612376/
https://ncbi.nlm.nih.gov/pubmed/18971263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01521-08
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