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African Swine Fever Virus Blocks the Host Cell Antiviral Inflammatory Response through a Direct Inhibition of PKC-θ-Mediated p300 Transactivation

During a viral infection, reprogramming of the host cell gene expression pattern is required to establish an adequate antiviral response. The transcriptional coactivators p300 and CREB binding protein (CBP) play a central role in this regulation by promoting the assembly of transcription enhancer co...

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Bibliografiske detaljer
Main Authors: Granja, Aitor G., Sánchez, Elena G., Sabina, Prado, Fresno, Manuel, Revilla, Yolanda
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2612362/
https://ncbi.nlm.nih.gov/pubmed/19004945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01663-08
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