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Identification of Sequences in Herpes Simplex Virus Type 1 ICP22 That Influence RNA Polymerase II Modification and Viral Late Gene Expression

Previous studies have shown that the herpes simplex virus type 1 (HSV-1) immediate-early protein ICP22 alters the phosphorylation of the host cell RNA polymerase II (Pol II) during viral infection. In this study, we have engineered several ICP22 plasmid and virus mutants in order to map the ICP22 se...

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Autori principali: Bastian, Thomas W., Rice, Stephen A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2612302/
https://ncbi.nlm.nih.gov/pubmed/18971282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01954-08
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