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T-Cell Responses to the Trypanosome Variant Surface Glycoprotein Are Not Limited to Hypervariable Subregions

Variable subregions within the variant surface glycoprotein (VSG) coat displayed by African trypanosomes are predicted sites for T- and B-cell recognition. Hypervariable subregion 1 (HV-1) is localized to an internal amphipathic alpha helix in VSG monomers and may have evolved due to selective press...

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Detalhes bibliográficos
Main Authors: Dagenais, Taylor R., Demick, Karen P., Bangs, James D., Forest, Katrina T., Paulnock, Donna M., Mansfield, John M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2612290/
https://ncbi.nlm.nih.gov/pubmed/18936180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00729-08
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