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A Hemidominant Naip5 Allele in Mouse Strain MOLF/Ei-Derived Macrophages Restricts Legionella pneumophila Intracellular Growth

Mouse-derived macrophages have the unique ability to restrict or permit Legionella pneumophila intracellular growth. The common inbred mouse strain C57BL/6J (B6) restricts L. pneumophila growth, whereas macrophages derived from A/J mice allow >10(3)-fold bacterial growth within three days. This p...

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Detalhes bibliográficos
Main Authors: Losick, Vicki P., Stephan, Kristin, Smirnova, Irina I., Isberg, Ralph R., Poltorak, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2612277/
https://ncbi.nlm.nih.gov/pubmed/18981241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01011-08
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