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The C-Type Lectin SIGNR1 Binds Schistosoma mansoni Antigens In Vitro, but SIGNR1-Deficient Mice Have Normal Responses during Schistosome Infection

The de novo immune response to infectious organisms arises from the innate recognition of pathogen-associated molecular patterns (PAMPs) by the host's pattern recognition receptors (PRRs). As the generation of type 2 cytokine responses by the human trematode parasite Schistosoma mansoni is glyc...

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Autors principals: Saunders, Sean P., Walsh, Caitriona M., Barlow, Jillian L., Mangan, Niamh E., Taylor, Philip R., McKenzie, Andrew N. J., Smith, Philip, Fallon, Padraic G.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2612259/
https://ncbi.nlm.nih.gov/pubmed/18981244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00762-08
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