Inhaled delivery of 23-valent pneumococcal polysaccharide vaccine does not result in enhanced pulmonary mucosal immunoglobulin responses

We compared the effect of intramuscular vs. inhaled 23-valent pneumococcal capsular polysaccharide vaccine (23-PPV) on pulmonary mucosal immunoglobulin levels. Bronchoalveolar lavage (BAL) and serum were collected from 33 adults before and 1 month after injected (n = 16) or inhaled (n = 17) 23-PPV....

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Main Authors: Gordon, Stephen B., Malamba, Rose, Mthunthama, Neema, Jarman, Elizabeth R., Jambo, Kondwani, Jere, Khuzwayo, Zijlstra, Eduard E., Molyneux, Malcolm E., Dennis, John, French, Neil
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Science 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2612086/
https://ncbi.nlm.nih.gov/pubmed/18708114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2008.07.082
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