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Genetic Evidence for the Essential Role of PfNT1 in the Transport and Utilization of Xanthine, Guanine, Guanosine and Adenine by Plasmodium falciparum
The malaria parasite, Plasmodium falciparum, is unable to synthesize the purine ring de novo and is therefore wholly dependent upon purine salvage from the host for survival. Previous studies have indicated that a P. falciparum strain in which the purine transporter PfNT1 had been disrupted was unab...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2612043/ https://ncbi.nlm.nih.gov/pubmed/18639591 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molbiopara.2008.06.012 |
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