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Sensitization of ovarian cancer cells to cisplatin by genistein: the role of NF-kappaB

BACKGROUND: Platinum-resistance (PR) continues to be a major problem in the management of epithelial ovarian cancer (EOC). Response to various chemotherapeutic agents is poor in patients deemed PR. Genistein, a soy isoflavone has been shown to enhance the effect of chemotherapy in prostate and pancr...

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Hlavní autoři: Solomon, Leigh A, Ali, Shadan, Banerjee, Sanjeev, Munkarah, Adnan R, Morris, Robert T, Sarkar, Fazlul H
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2611983/
https://ncbi.nlm.nih.gov/pubmed/19025644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1757-2215-1-9
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