ptena and ptenb Genes Play Distinct Roles in Zebrafish Embryogenesis

PTEN is a tumor suppressor gene associated with multiple tumor types. PTEN function is essential for early embryonic development and is involved in the regulation of cell size, number, and survival. By dephosphorylating PIP(3), PTEN normally acts to inhibit the PI3-Kinase/AKT pathway. Here we have i...

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Main Authors: Croushore, Jessica A., Blasiole, Brian, Riddle, Ryan C., Thisse, Christine, Thisse, Bernard, Canfield, Victor A., Robertson, Gavin P., Cheng, Keith, Levenson, Robert
Formato: Artigo
Idioma:Inglês
Publicado: 2005
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2611959/
https://ncbi.nlm.nih.gov/pubmed/16193492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.20576
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