ptena and ptenb Genes Play Distinct Roles in Zebrafish Embryogenesis

PTEN is a tumor suppressor gene associated with multiple tumor types. PTEN function is essential for early embryonic development and is involved in the regulation of cell size, number, and survival. By dephosphorylating PIP(3), PTEN normally acts to inhibit the PI3-Kinase/AKT pathway. Here we have i...

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Autores principales: Croushore, Jessica A., Blasiole, Brian, Riddle, Ryan C., Thisse, Christine, Thisse, Bernard, Canfield, Victor A., Robertson, Gavin P., Cheng, Keith, Levenson, Robert
Formato: Artigo
Lenguaje:Inglês
Publicado: 2005
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2611959/
https://ncbi.nlm.nih.gov/pubmed/16193492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.20576
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