Acetylated lysine 56 on histone H3 drives chromatin assembly after repair, signaling for the completion of repair

The mechanisms whereby chromatin structure and cell cycle progression are restored after DNA repair are largely unknown. We show that chromatin is reassembled following double-strand break (DSB) repair and that this requires the histone chaperone Asf1. Absence of Asf1 causes persistent activation of...

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Bibliographic Details
Main Authors: Chen, Chin-Chuan, Carson, Joshua J., Feser, Jason, Tamburini, Beth, Zabaronick, Susan, Linger, Jeffrey, Tyler, Jessica K.
Format: Artigo
Language:Inglês
Published: 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2610811/
https://ncbi.nlm.nih.gov/pubmed/18662539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2008.06.035
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