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Functional characterization of cohesin subunit SCC1 in Trypanosoma brucei and dissection of mutant phenotypes in two life cycle stages

In yeast and metazoa, structural maintenance of chromosome (SMC) complexes play key roles in chromosome segregation, architecture and DNA repair. The main function of the cohesin complex is to hold replicated sister chromatids together until segregation at anaphase, which is dependent on proteolytic...

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Bibliographic Details
Main Authors: Gluenz, Eva, Sharma, Reuben, Carrington, Mark, Gull, Keith
Format: Artigo
Language:Inglês
Published: Blackwell Publishing Ltd 2008
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2610385/
https://ncbi.nlm.nih.gov/pubmed/18554326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2008.06320.x
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