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Levels of Foxp3 in regulatory T cells reflect their functional status in transplantation

Foxp3 expressing CD4+CD25+ regulatory T cells (Tregs) have been shown to prevent allograft rejection in clinical and animal models of transplantation. However, the role of Foxp3 in regulating Treg function, and the kinetics and mechanism of action of Tregs in inducing allograft tolerance in transpla...

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Autori principali: Chauhan, Sunil K, Saban, Daniel R, Lee, Hyung K, Dana, Reza
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2610348/
https://ncbi.nlm.nih.gov/pubmed/19109145
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