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Total Synthesis of (+)-Batzelladine A and (−)-Batzelladine D via [4 + 2]-Annulation of Vinyl Carbodiimides with N-Alkyl Imines

A diastereoselective [4 + 2]-annulation of vinyl carbodiimides with chiral N-alkyl imines has been developed to access the stereochemically rich polycyclic guanidine cores of the batzelladine alkaloids. Application of this strategy, together with additional key steps such as long-range directed hydr...

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Detalhes bibliográficos
Main Authors: Arnold, Michael A., Day, Kenneth A., Durón, Sergio G., Gin, David Y.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2610335/
https://ncbi.nlm.nih.gov/pubmed/17017806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja063860+
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