A preclinical evaluation of aminopyridines as putative therapeutic agents in the treatment of botulism.
4-Aminopyridine and 3,4-diaminopyridine were evaluated for their abilities to delay the onset of paralysis due to botulinum neurotoxin types A, B, and E. Experiments were done on phrenic nerve-hemidiaphragm preparations excised from mice. At a concentration that produced an enhancement in muscle twi...
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| Publicado no: | Infect Immun |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
1986
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC260939/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3011675/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.52.3.858-862.1986 |
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