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Pathogenesis of Shigella diarrhea: rabbit intestinal cell microvillus membrane binding site for Shigella toxin.

This study examined the binding of purified 125I-labeled shigella toxin to rabbit jejunal microvillus membranes (MVMs). Toxin binding was concentration dependent, saturable, reversible, and specifically inhibited by unlabeled toxin. The calculated number of toxin molecules bound at 4 degrees C was 7...

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Detalhes bibliográficos
Main Authors: Fuchs, G, Mobassaleh, M, Donohue-Rolfe, A, Montgomery, R K, Grand, R J, Keusch, G T
Formato: Artigo
Idioma:Inglês
Publicado em: 1986
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC260885/
https://ncbi.nlm.nih.gov/pubmed/3755421
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