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Adjuvant activity of 6-O-acyl-muramyldipeptides to enhance primary cellular and humoral immune responses in guinea pigs: dose-response and local reactions observed with selected compounds.

6-O-(2-Tetradecylhexadecanoyl)-N-acetylmuramyl-L-alanyl-D-isoglutamine (B3O-MDP) and 6-O-(3-hydroxy-2-docosylhexacosanoyl)-MDP (BH48-MDP) were examined for immunopotentiating activity in stimulating the primary immune responses of guinea pigs to ovalbumin and for adverse reactions at the injection s...

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Vydáno v:Infect Immun
Hlavní autoři: Tsujimoto, M, Kotani, S, Shiba, T, Kusumoto, S
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 1986
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC260820/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3744549/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.53.3.517-521.1986
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