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Adjuvant activity of 6-O-acyl-muramyldipeptides to enhance primary cellular and humoral immune responses in guinea pigs: adaptability to various vehicles and pyrogenicity.

Thirteen 6-O-acyl-N-acetylmuramyl-L-alanyl-D-isoglutamines (6-O-acyl-MDPs), including four inactive D-isoasparagine and L-isoglutamine analogs, were tested for their pyrogenicity and immunopotentiating activity to stimulate primary humoral and cellular immune responses in guinea pigs to a model prot...

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Bibliographic Details
Published in:Infect Immun
Main Authors: Tsujimoto, M, Kotani, S, Kinoshita, F, Kanoh, S, Shiba, T, Kusumoto, S
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1986
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Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC260819/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3744548/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.53.3.511-516.1986
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