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Inactivation of botulinum and tetanus toxins by chelators.

Purified type A botulinum toxin of about 10(6) mouse 50% lethal doses per ml was greater than 99.9% inactivated when incubated at pH 7.4 for 30 min at 37 degrees C in 20 mM 1,10-phenanthroline (PTL) or 2,2'-dipyridyl (DPD) and was 96% inactivated when incubated in 70 mM 8-hydroxyquinoline-5-sul...

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Détails bibliographiques
Auteurs principaux: Bhattacharyya, S D, Sugiyama, H
Format: Artigo
Langue:Inglês
Publié: 1989
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC260769/
https://ncbi.nlm.nih.gov/pubmed/2506129
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