A carregar...

Gain of Function Mutations in CgPDR1 of Candida glabrata Not Only Mediate Antifungal Resistance but Also Enhance Virulence

CgPdr1p is a Candida glabrata Zn(2)-Cys(6) transcription factor involved in the regulation of the ABC-transporter genes CgCDR1, CgCDR2, and CgSNQ2, which are mediators of azole resistance. Single-point mutations in CgPDR1 are known to increase the expression of at least CgCDR1 and CgCDR2 and thus to...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Ferrari, Sélène, Ischer, Françoise, Calabrese, David, Posteraro, Brunella, Sanguinetti, Maurizio, Fadda, Giovanni, Rohde, Bettina, Bauser, Christopher, Bader, Oliver, Sanglard, Dominique
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2607542/
https://ncbi.nlm.nih.gov/pubmed/19148266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000268
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!