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Novel Soluble Flt-1 Isoforms in Plasma and Cultured Placental Explants from Normotensive Pregnant and Preeclamptic Women

Pregnant women who develop preeclampsia exhibit higher circulating levels of the soluble VEGF receptor-1 (sFlt-1). Recent findings suggest that soluble Flt-1 may contribute to the pathogenesis of preeclampsia by binding and neutralizing vascular endothelial growth factors (VEGF) and placental growth...

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Hlavní autoři: Rajakumar, A., Powers, R.W., Hubel, C.A., Shibata, E., von Versen-Höynck, F., Plymire, D., Jeyabalan, A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2607481/
https://ncbi.nlm.nih.gov/pubmed/19010535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.placenta.2008.10.006
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