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Testing the hypothesis that amphiphilic antineoplastic lipid analogues act through reduction of membrane curvature elastic stress

The alkyllysophospholipid (ALP) analogues Mitelfosine and Edelfosine are anticancer drugs whose mode of action is still the subject of debate. It is agreed that the primary interaction of these compounds is with cellular membranes. Furthermore, the membrane-associated protein CTP: phosphocholine cyt...

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Bibliografische gegevens
Hoofdauteurs: Dymond, Marcus, Attard, George, Postle, Anthony D
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Royal Society 2008
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2607441/
https://ncbi.nlm.nih.gov/pubmed/18426775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2008.0041
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