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Unsupervised reduction of random noise in complex data by a row-specific, sorted principal component-guided method

BACKGROUND: Large biological data sets, such as expression profiles, benefit from reduction of random noise. Principal component (PC) analysis has been used for this purpose, but it tends to remove small features as well as random noise. RESULTS: We interpreted the PCs as a mere signal-rich coordina...

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Detalhes bibliográficos
Main Authors: Foley, Joseph W, Katagiri, Fumiaki
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2607290/
https://ncbi.nlm.nih.gov/pubmed/19040754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-9-508
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