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From protein interactions to functional annotation: graph alignment in Herpes

BACKGROUND: Sequence alignment is a prolific basis of functional annotation, but remains a challenging problem in the 'twilight zone' of high sequence divergence or short gene length. Here we demonstrate how information on gene interactions can help to resolve ambiguous sequence alignments...

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Bibliografiske detaljer
Main Authors: Kolář, Michal, Lässig, Michael, Berg, Johannes
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2607256/
https://ncbi.nlm.nih.gov/pubmed/18957106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-2-90
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