Dexamethasone potentiates the antiangiogenic activity of docetaxel in castration-resistant prostate cancer

We sought to characterise whether dexamethasone (DEX) may enhance tumour response to docetaxel in in vitro and in vivo models of metastatic prostate cancer (CaP). In vitro experiments conducted on PC3 and human bone marrow endothelial cells (hBMECs) determined that administration of DEX (10 nM) redu...

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Detalhes bibliográficos
Main Authors: Wilson, C, Scullin, P, Worthington, J, Seaton, A, Maxwell, P, O'Rourke, D, Johnston, P G, McKeown, S R, Wilson, R H, O'Sullivan, J M, Waugh, D J J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
Assuntos:
Molecular Diagnostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2607236/
https://ncbi.nlm.nih.gov/pubmed/19050703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604804
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