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An endogenous regulator of inflammation, resolvin E1, modulates osteoclast differentiation and bone resorption

BACKGROUND AND PURPOSE: The inflammation-resolving lipid mediator resolvin E1 (RvE1) effectively stops inflammation-induced bone loss in vivo in experimental periodontitis. It was of interest to determine whether RvE1 has direct actions on osteoclast (OC) development and bone resorption. EXPERIMENTA...

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Detalhes bibliográficos
Main Authors: Herrera, B S, Ohira, T, Gao, L, Omori, K, Yang, R, Zhu, M, Muscara, M N, Serhan, C N, Van Dyke, T E, Gyurko, R
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2607210/
https://ncbi.nlm.nih.gov/pubmed/18806821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.367
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