Protective action of doxycycline against diabetic cardiomyopathy in rats

BACKGROUND AND PURPOSE: Reactive oxygen and nitrogen species play an important role in the development of diabetic cardiomyopathy. They can activate matrix metalloproteinases (MMPs), and MMP-2 in particular is known to mediate early consequences of oxidative stress injury in the heart. Therefore, we...

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Detalhes bibliográficos
Main Authors: Yaras, N, Sariahmetoglu, M, Bilginoglu, A, Aydemir-Koksoy, A, Onay-Besikci, A, Turan, B, Schulz, R
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2607202/
https://ncbi.nlm.nih.gov/pubmed/18806806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.373
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