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Modulation of Thiol-Disulfide Oxidoreductases for Increased Production of Disulfide-Bond-Containing Proteins in Bacillus subtilis

Disulfide bonds are important for the correct folding, structural integrity, and activity of many biotechnologically relevant proteins. For synthesis and subsequent secretion of these proteins in bacteria, such as the well-known “cell factory” Bacillus subtilis, it is often the correct formation of...

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Autori principali: Kouwen, Thijs R. H. M., Dubois, Jean-Yves F., Freudl, Roland, Quax, Wim J., van Dijl, Jan Maarten
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2607156/
https://ncbi.nlm.nih.gov/pubmed/18952880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.00894-08
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