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Host inactivation of bacterial lipopolysaccharide prevents prolonged microbial tolerance following Gram-negative bacterial infection

A transient state of tolerance to microbial molecules accompanies many infectious diseases. Thought to minimize inflammation-induced injury, it may also alter host defenses. Here we report that recovery from the tolerant state induced by Gram-negative bacteria is greatly delayed in mice that lack ac...

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Autori principali: Lu, Mingfang, Varley, Alan W., Ohta, Shoichiro, Hardwick, John, Munford, Robert S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2607035/
https://ncbi.nlm.nih.gov/pubmed/18779055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2008.06.009
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