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Coordinated control of self-renewal and differentiation of neural stem cells by Myc and the p19(ARF)–p53 pathway
The modes of proliferation and differentiation of neural stem cells (NSCs) are coordinately controlled during development, but the underlying mechanisms remain largely unknown. In this study, we show that the protooncoprotein Myc and the tumor suppressor p19(ARF) regulate both NSC self-renewal and t...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2606961/ https://ncbi.nlm.nih.gov/pubmed/19114593 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200807130 |
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