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YC-1 Stimulates the Expression of Gaseous Monoxide-Generating Enzymes in Vascular Smooth Muscle Cells

The benzylindazole derivative 3-(5′-hydroxymethyl-2′-furyl)-1-benzyl indazole (YC-1) is an allosteric stimulator of soluble guanylate cyclase (sGC) that sensitizes the enzyme to the gaseous ligands carbon monoxide (CO) and nitric oxide (NO). In this study, we examined whether YC-1 also promotes the...

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Bibliografiske detaljer
Main Authors: Liu, Xiao-ming, Peyton, Kelly J., Mendelev, Natalia N., Wang, Hong, Tulis, David A., Durante, William
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Pharmacology and Experimental Therapeutics 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2606927/
https://ncbi.nlm.nih.gov/pubmed/18923065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.108.048314
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